Autopsy keeps running for days even when 100% is showed

Left the app running for 10 days after 100% was displayed, is it normal?
If I run several cases on the same PC (Win 10 Pro) i saw the c:\Users\Appdata\Roaming\Central_Repository\central_repository.db continues to increment its size and
Keywordsearch function looks for something that was in another case.
Is there a way to clean-up that file before running new case?
Many thanks