I have a new download and install of Autopsy 4.15.0 on a Windows 10 box.
Dual Xeon processors and 65GB RAM
The program begins to launch and the status bar progresses about 2/3 before the whole process disappears. There is no error message or problem indicator.
I have rebooted and retried with it failing at the same point.
I have uninstalled and reinstalled with the same issue.